From the “old NEC” to the “new NECs”

Melania Puddu, Maria Antonietta Marcialis, Anna De Magistris, Roberta Irmesi, Elisabetta Coni, Luigi Mascia, Vassilios Fanos


Necrotizing enterocolitis (NEC) is an acute inflammatory disease of the neonatal intestine that strikes in 1 of 1,000 live births. Its etiology is unknown.  This review describes in detail the new NECs especially those which affect preterm infants: contagion or lymphocytosis associated, transfusion associated and cow’s milk allergy associated. A wide repertory of images are presented, together with algorithms for differential diagnosis.


Proceedings of the International Course on Perinatal Pathology (part of the 10th International Workshop on Neonatology · October 22nd-25th, 2014) · Cagliari (Italy) · October 25th, 2014 · The role of the clinical pathological dialogue in problem solving

Guest Editors: Gavino Faa, Vassilios Fanos, Peter Van Eyken


necrotizing enterocolitis; intestinal mucosa barrier; NEC sub-classes; prevention; gastrointestinal neonatal problems

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