Severe renal damage in a 21-month-old child: question

Alice Sanna, Clara Gerosa, Rossano Ambu, Melania Puddu, Anna Maria Nurchi, Gavino Faa


A male child aged 21 months was admitted fifteen days after abdominal pain and vomits. At clinical examination, he had a pale skin, erythematous eruptions on the arms and abdomen, edema of the eyelids and feet, whitish patches on the oral mucosa of the cheek, hypertrophic tonsils and latero cervical lymphadenopathy. Laboratory tests were within the normal range. The patient was not febrile. A few days later, the child’s general condition worsened and fever appeared. Seven days after admission, the child showed a skin rash on the face. He received several drugs, including aspirin and antibiotics. The patient general condition continued to worsen (body weight decreased, blood pressure and fever increased) until death.

1. Which is your macroscopic diagnosis?

2. Which is your histological diagnosis?


quiz; polyarteritis nodosa; child; kidney

Full Text: PDF Number of abstract views: 3350 Number of PDF views/downloads: 2576


N.B. All JPNIM articles are accessible in Open Access. You can access the page containing the full PDF article just by clicking on the “Full Text: PDF” link at the bottom of the abstract page. On the full article page, if the article doesn’t load properly in the PDF view window, please wait a few seconds or click on the “Download this PDF file” link.

Technical advice. If you are using Firefox and you are experiencing problems, please set the browser preferences as follows: Firefox > Preferences > Advanced > General > Accessibility > deselect "Warn me when web sites try to redirect or reload the page".

Privacy Policy. English text: Privacy Policy; Italian text: Privacy Policy.

Cookie Policy. English text: Cookie Policy; Italian text: Cookie Policy.